Lénaic MONCONDUIT (EN)

NEURO-DOL – UMR1107 INSERM/UCA
2, rue de Braga, 63100, Clermont-Ferrand (FRANCE)

Dr. Lénaic MONCONDUIT

Assistant Professor
Team TPM – Pathophysiology of migraine axis, Team TPM – Therapeutic Targets and Technological Innovations Axis, Team TPM -Technical Advances, Team Trigeminal Pain and Migraine

lenaic.monconduit@-Code to remove to avoid SPAM-uca.fr
+33 4 73 17 73 14, room 241

Student :

Chloé Barrat

Research Theme:

Pathophysiology of migraine axis
My research theme concerns the study of factors that can promote the occurrence of migraine attacks. I am particularly interested in the alteration of descending pain controls in the context of this pathology and the influence of hormones in the evolution of migraine attacks.

Techniques Used:

extracellular electrophysiology, immunohistochemistry, viruses, behavior

Teachings:

Human physiology, pathophysiology of pain in LAS/PASS, license, 2nd year of odontology, master 1.

Image:

HAL Publications

Journal articles

2023

ref_biblio: Jérémy Signoret-Genest, Maxime Barnet, François Gabrielli, Youssef Aissouni, Alain Artola, et al.. Compromised trigemino-coerulean coupling in migraine sensitization can be prevented by blocking beta-receptors in the locus coeruleus. Journal of Headache and Pain, 2023, 24 (1), pp.165. ⟨10.1186/s10194-023-01691-1⟩. ⟨hal-04331348⟩
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2020

ref_biblio: Julie Duron, Lénaïc Monconduit, Paul Avan. Auditory Brainstem Changes in Timing may Underlie Hyperacusis in a Salicylate-induced Acute Rat Model. Neuroscience, 2020, 426, pp.129-140. ⟨10.1016/j.neuroscience.2019.11.038⟩. ⟨hal-02467722⟩
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2018

ref_biblio: Cristina Alba-Delgado, Sarah Mountadem, Noémie Mermet-Joret, Lénaïc Monconduit, Radhouane Dallel, et al.. 5-HT 2A Receptor-Induced Morphological Reorganization of PKCγ-Expressing Interneurons Gates Inflammatory Mechanical Allodynia in Rat. Journal of Neuroscience, 2018, 38 (49), pp.10489-10504. ⟨10.1523/JNEUROSCI.1294-18.2018⟩. ⟨hal-04326313⟩
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2017

ref_biblio: Nelly Boyer, Jérémy Signoret-Genest, Alain Artola, Radhouane Dallel, Lénaïc Monconduit. Propranolol treatment prevents chronic central sensitization induced by repeated dural stimulation. Pain, 2017, 158 (10), pp.2025 – 2034. ⟨10.1097/j.pain.0000000000001007⟩. ⟨hal-01680695⟩
Accès au bibtex

ref_biblio: Noemie Mermet-Joret, Nadwa Chatila, Bruno Pereira, Lénaïc Monconduit, Radhouane Dallel, et al.. Lamina specific postnatal development of PKCγ interneurons within the rat medullary dorsal horn. Developmental Neurobiology, 2017, 77 (1), pp.102 – 119. ⟨10.1002/dneu.22414⟩. ⟨hal-01680753⟩
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2015

ref_biblio: Khaled Abdallah, Lénaïc Monconduit, Alain Artola, Philippe Luccarini, Radhouane Dallel. GABAAergic inhibition or dopamine denervation of the A11 hypothalamic nucleus induces trigeminal analgesia. Pain, 2015, 156 (4), pp.644 – 655. ⟨10.1097/j.pain.0000000000000091⟩. ⟨hal-01836230⟩
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2013

ref_biblio: Khaled Abdallah, Alain Artola, Lénaïc Monconduit, Radhouane Dallel, Philippe Luccarini, et al.. Bilateral Descending Hypothalamic Projections to the Spinal Trigeminal Nucleus Caudalis in Rats. PLoS ONE, 2013, 8 (8), ⟨10.1371/journal.pone.0073022⟩. ⟨hal-01836269⟩
Accès au bibtex

2011

ref_biblio: Laurent Devoize, Pédro Alvarez, Lénaïc Monconduit, Radhouane Dallel. Representation of dynamic mechanical allodynia in the ventral medial prefrontal cortex of trigeminal neuropathic rats. European Journal of Pain, 2011, 15 (7), pp.676-682. ⟨10.1016/j.ejpain.2010.11.017⟩. ⟨hal-03626179⟩
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ref_biblio: Olivier Lapirot, Céline Melin, Alice Modolo, Charline Nicolas, Yassine Messaoudi, et al.. Tonic and phasic descending dopaminergic controls of nociceptive transmission in the medullary dorsal horn. Pain, 2011, 152 (8), pp.1821 – 1831. ⟨10.1016/j.pain.2011.03.030⟩. ⟨hal-01836275⟩
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2005

ref_biblio: Michaël Zugaro, Lénaïc Monconduit, György Buzsáki. Spike phase precession persists after transient intrahippocampal perturbation.. Nature Neuroscience, 2005, 8 (1), pp.67-71. ⟨10.1038/nn1369⟩. ⟨hal-00599394⟩
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Conference papers

2019

ref_biblio: P. Luccarini, Marine Megemont, Amélie Descheemaeker, Radhouane Dallel, L. Monconduit. Astrocytes contribute to the trigeminal central sensitization and cephalic cutaneous hypersensitivity in rat model of chronic migraine.. NeuroFrance 2019 Congress, 23-24 mai 2019, Marseille (France)., Société des neurosciences, May 2019, MARSEILLE, France. ⟨hal-04605880⟩
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ref_biblio: Marine Megemont, Amélie Descheemaeker, Radhouane Dallel, L. Monconduit, P. Luccarini. Astrocytes contribute to the trigeminal central sensitization and cephalic cutaneous hypersensitivity in rat model of chronic migraine.. 15th Symposium de la Recherche du Réseau Douleur, Mar 2019, Paris, France. ⟨hal-04605879⟩
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2017

ref_biblio: Saba Amirdehi, Khalil El Khamlichi Drissi, Christophe Pasquier, Lénaïc Monconduit, Benoit Sion, et al.. Analysis of electrophysiological activities using Matrix Pencil Method. IEEE EUROCON 2017 -17th International Conference on Smart Technologies, Jul 2017, Ohrid, Macedonia. pp.531-536. ⟨hal-01658269⟩
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2010

ref_biblio: P. Luccarini, Olivier Lapirot, Alice Modolo, Claire Villemain, Charline Nicolas, et al.. Superficial medullary dorsal horn dopamine D2 receptors modulate mainly trigeminal C-fiber nociceptive transmission. 13th World Congress on Pain, IASP, Aug 2010, Montréal (Québec), Canada. ⟨hal-04605893⟩
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Poster communications

2020

ref_biblio: François Gabrielli, Baptiste Sion, Zied Mizouri, Lénaïc Monconduit, Benoit Sion, et al.. Closed-loop control of nervous response. International Neuroscience Conference, Jul 2020, Marseille, France. ⟨hal-03086412⟩
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