Karine HERAULT (EN)
NEURO-DOL – UMR1107 INSERM/UCA
2, rue de Braga, 63100, Clermont-Ferrand (FRANCE)
Karine HERAULT
Engineer
Team Trigeminal Pain and Migraine
karine.herault@-Code to remove to avoid SPAM-inserm.fr
+33 4 73 17 73 67, room 244
Biography:
From 2008 to 2013, I worked in the Neurophysiology and New Microscopies laboratory in the laboratory of Serge Charpak, in the Ropert/Oheim team. Since 2014, I have joined the Neuro Dol laboratory in Pr. Dallel’s team. I participate in various research projects of the team, in particular on the role of astrocytes in inflammatory skin hypersensitivity and migraine in rodents.
Technical skills:
- SDS Page and WB
- Cell culture (cell lines; murine neurons and astrocytes)
- Immunolabeling (murine brain and marrow)
- Analysis behavioral (chronic inflammatory, neuropathic and migraine pain model in rats)
- Surgery
- Microscopy (confocal and epifluorescence microscope)
- Training for new arrivals
Functions:
- Master Pro Physiology Cellular and Molecular Biology PBCM Poitiers (2007)
- INSERM study engineer (2009)
Responsibilities:
- Prevention and OHS Assistant
- Member of the Animal Welfare Structure (SBEA)
- GMO
- Member of the CLAS INSERM office Auvergne Rhône Alpes
Image:
HAL Publications
Journal articles
2025
- ref_biblio
- Sarah Mountadem, Karine Hérault, Cedric Peirs, Gisela da Silva Borges, Daniel Voisin, et al.. Astrocytic Kir4.1 ion channel deficit drives persistent inflammatory facial pain in males. Brain – A Journal of Neurology , 2025, ⟨10.1093/brain/awaf122⟩. ⟨hal-05035061⟩
- Accès au bibtex
-
2021
- ref_biblio
- Cuong Pham, Karine Hérault, Martin Oheim, Steeve Maldera, Vincent Vialou, et al.. Astrocytes respond to a neurotoxic Aβ fragment with state-dependent Ca 2+ alteration and multiphasic transmitter release. Acta Neuropathologica Communications, 2021, 9 (1), pp.44. ⟨10.1186/s40478-021-01146-1⟩. ⟨hal-03182439⟩
- Accès au texte intégral et bibtex
-
- ref_biblio
- Alexia Visseq, Amélie Descheemaeker, Karine Hérault, Francis Giraud, Isabelle Abrunhosa-Thomas, et al.. Improved potency of pyridin-2(1H)one derivatives for the treatment of mechanical allodynia. European Journal of Medicinal Chemistry, 2021, 225, pp.113748. ⟨10.1016/j.ejmech.2021.113748⟩. ⟨hal-03334145⟩
- Accès au texte intégral et bibtex
-
2015
- ref_biblio
- Dongdong Li, Karine Hérault, Kathleen Zylbersztejn, Marcel A Lauterbach, Marc Guillon, et al.. Astrocyte VAMP3 vesicles undergo Ca2+ -independent cycling and modulate glutamate transporter trafficking.. The Journal of Physiology, 2015, 593 (13), pp.2807-32. ⟨10.1113/JP270362⟩. ⟨hal-01266219⟩
- Accès au bibtex
-
2014
- ref_biblio
- Maia Brunstein, Karine Hérault, Martin Oheim. Eliminating Unwanted Far-Field Excitation in Objective-Type TIRF. Part II. Combined Evanescent-Wave Excitation and Supercritical-Angle Fluorescence Detection Improves Optical Sectioning. Biophysical Journal, 2014, 106 (5), pp.1044-1056. ⟨10.1016/j.bpj.2013.12.051⟩. ⟨hal-04136748⟩
- Accès au bibtex
-
- ref_biblio
- Maia Brunstein, Maxime Teremetz, Karine Hérault, Christophe Tourain, Martin Oheim. Eliminating Unwanted Far-Field Excitation in Objective-Type TIRF. Part I. Identifying Sources of Nonevanescent Excitation Light. Biophysical Journal, 2014, 106 (5), pp.1020-1032. ⟨10.1016/j.bpj.2013.12.049⟩. ⟨hal-04136747⟩
- Accès au bibtex
-
2013
- ref_biblio
- Maia Brunstein, Kai Wicker, Karine Hérault, Rainer Heintzmann, Martin Oheim. Full-field dual-color 100-nm super-resolution imaging reveals organization and dynamics of mitochondrial and ER networks. Optics Express, 2013, 21 (22), pp.26162. ⟨10.1364/oe.21.026162⟩. ⟨hal-04136753⟩
- Accès au bibtex
-
- ref_biblio
- Dongdong Li, Karine Herault, Kaetlin Silm, Alexis Evrard, Sonja Wojcik, et al.. Lack of Evidence for Vesicular Glutamate Transporter Expression in Mouse Astrocytes. Journal of Neuroscience, 2013, 33 (10), pp.4434-4455. ⟨10.1523/JNEUROSCI.3667-12.2013⟩. ⟨hal-01542733⟩
- Accès au bibtex
-
Poster communications
2023
- ref_biblio
- P. Moreau, A. Visseq, A. Descheemaeker, N. Pinto-Pardo, K. Herault, et al.. Development of pyridin-2(1H)-one derivatives with in vivo activity toward mechanical allodynia.. 3rd RSC Anglo-Nordic Medicinal Chemistry Symposium, Jun 2023, Snekkersten, Denmark. ⟨hal-04563721⟩
- Accès au bibtex
-