Gisèle PICKERING (EN)

UMR 1107 INSERM/UCA Neuro-Dol
Facultés de Médecine et Pharmacie
Place Henri Dunant
63001 Clermont-Ferrand
FRANCE

Pr. Gisèle PICKERING

Professor
Fundamental Pharmacology and Pain Clinic Team, Team FPPC – Pain and Cancer Axis, Team FPPC- Axe Patient

gisele.pickering@-Code to remove to avoid SPAM-uca.fr

Research Theme:

  • Physiopathology and Pharmacology of pain (Fibromyalgia syndrome, cancer pain, neuropathic pain)
  • Identification of predictive factors for the development of chronic pain
  • Validation of tools pain assessment

Teachings:

  • Pain teaching
  • Pharmacology teaching
  • Supervision of Doctoral and Masters students

Responsibilities:

  • Chef de Service de la Plateforme d’Investigation Clinique, CIC Inserm 1405
  • Directrice du CIC Inserm 1405

Recent article selections:

  • Clarke et al. Systematic review and co-ordinate based meta-analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensitization. Eur J Pain. 2024 Feb 21. doi: 10.1002/ejp.2251.
  • Pickering et al. Effectiveness and safety of 5% lidocaine-medicated plaster on localized neuropathic pain after knee surgery: a randomized, double-blind controlled trial. Pain. 2019 May; 160(5):1186-1195. PMID: 31009419
  • Voute M et al., Assessment of Initial Depressive State and Pain Relief With Ketamine in Patients With Chronic Refractory Pain. JAMA Netw Open. 2023 May 1; 6(5):e2314406. PMID: 37204789

Additional Information:

ORCID : 0000-0001-9054-9379

HAL Publications

Journal articles

2023

ref_biblio
Fabien Wauquier, Doriane Ripoche, Line Boutin-Wittrant, Yolanda F Otero, Florian Le Joubioux, et al.. Circulating bioactives resulting from totum-854 absorption in humans protects primary human endothelial cells against lipotoxicity: lessons from an original ex vivo clinical trial. Journal of Hypertension -Supplement-, 2023, 41, pp.E308-E308. ⟨hal-04323875⟩
Accès au bibtex

BibTex

2022

ref_biblio
Alexandrine Corriger, Marion Voute, Céline Lambert, Bruno Pereira, Gisèle Pickering. Ketamine for refractory chronic pain: a 1-year follow-up study. Pain, 2022, 163 (4), pp.690-701. ⟨10.1097/j.pain.0000000000002403⟩. ⟨hal-04256432⟩
Accès au bibtex

BibTex

2020

ref_biblio
Lionel Noah, Gisèle Pickering, André Mazur, Claude Dubray, Simon Hitier, et al.. Impact of magnesium supplementation, in combination with vitamin B6, on stress and magnesium status: secondary data from a randomized controlled trial. Magnesium Research, 2020, 33 (3), pp.45-57. ⟨10.1684/mrh.2020.0468⟩. ⟨hal-03042129⟩
Accès au texte intégral et bibtex

https://hal.inrae.fr/hal-03042129/file/2020_Noah_Magnesium_Res.pdf


BibTex

ref_biblio
Gisèle Pickering, André Mazur, Marion Trousselard, Przemyslaw Bienkowski, Natalia Yaltsewa, et al.. Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients, 2020, 12 (12), pp.3672. ⟨10.3390/nu12123672⟩. ⟨hal-03041446⟩
Accès au texte intégral et bibtex

https://hal.science/hal-03041446/file/2020_Pickering_Nutrients.pdf


BibTex

ref_biblio
Marion Voute, Véronique Morel, Dominique Joly, Christine Villatte, Elodie Martin, et al.. Predicting Pain Trajectories in the One Year Following Breast Cancer Diagnosis—An Observational Study. Journal of Clinical Medicine, 2020, 9 (6), pp.1907. ⟨10.3390/jcm9061907⟩. ⟨hal-02882206⟩
Accès au texte intégral et bibtex

https://hal.science/hal-02882206/file/jcm-09-01907-v2.pdf


BibTex

2019

ref_biblio
Alexandrine Corriger, Gisèle Pickering. Ketamine and depression: a narrative review. Drug Design, Development and Therapy, 2019, 13 (6), pp.3051-3067. ⟨10.2147/DDDT.S221437⟩. ⟨hal-04257286⟩
Accès au bibtex

BibTex
ref_biblio
Alexandrine Corriger, Martine Duclos, Jean-Benoît Corcuff, Céline Lambert, Geoffroy Marceau, et al.. Hormonal status and cognitivo‐emotional profile in real‐life neuropathic pain patients: a case control study. Pain Practice, 2019, 19 (7), ⟨10.1111/papr.12800⟩. ⟨hal-02193914⟩
Accès au bibtex

BibTex
ref_biblio
Elodie Martin, Marc Sorel, Véronique Morel, Fabienne Marcaillou, Pascale Picard, et al..

Dextromethorphan and memantine after ketamine analgesia: a randomized control trial

. Drug Design, Development and Therapy, 2019, Volume 13, pp.2677-2688. ⟨10.2147/DDDT.S207350⟩. ⟨hal-02325142⟩

Accès au bibtex

BibTex
ref_biblio
Rex Park, Anthony M-H Ho, Gisèle Pickering, Lars Arendt-Nielsen, Mohammed Mohiuddin, et al.. Magnesium for the Management of Chronic Noncancer Pain in Adults: Protocol for a Systematic Review. JMIR Research Protocols, 2019, 8 (1), pp.e11654. ⟨10.2196/11654⟩. ⟨hal-04257283⟩
Accès au bibtex

BibTex
ref_biblio
Rex Park, Anthony M-H Ho, Gisèle Pickering, Lars Arendt-Nielsen, Mohammed Mohiuddin, et al.. Magnesium for the Management of Chronic Noncancer Pain in Adults: Protocol for a Systematic Review. JMIR Research Protocols, 2019, 8 (1), pp.e11654. ⟨10.2196/11654⟩. ⟨hal-02324727⟩
Accès au bibtex

BibTex
ref_biblio
Gisèle Pickering, Marion Voute, Nicolas Macian, Hervé Ganry, Bruno Pereira. Effectiveness and safety of 5% lidocaine-medicated plaster on localized neuropathic pain after knee surgery. Pain, 2019, 160 (5), pp.1186-1195. ⟨10.1097/j.pain.0000000000001502⟩. ⟨hal-02325181⟩
Accès au bibtex

BibTex
ref_biblio
Gisèle Pickering, Isabelle Creveaux, Nicolas Macian, Bruno Pereira. Paracetamol and Pain Modulation by TRPV1, UGT2B15, SULT1A1 Genotypes: A Randomized Clinical Trial in Healthy Volunteers. Pain Medicine, 2019, ⟨10.1093/pm/pnz037⟩. ⟨hal-02325093⟩
Accès au bibtex

BibTex

2018

ref_biblio
Christian Dualé, Jean-Michel Cardot, Fabienne Joanny, Anna Trzeciakiewicz, Elodie Martin, et al.. An Advanced Formulation of a Magnesium Dietary Supplement Adapted for a Long-Term Use Supplementation Improves Magnesium Bioavailability: In Vitro and Clinical Comparative Studies. Biological Trace Element Research, 2018, 186 (1), pp.1-8. ⟨10.1007/s12011-018-1277-2⟩. ⟨hal-02460346⟩
Accès au bibtex

BibTex
ref_biblio
Gisèle Pickering, Nicolas Macian, Noémie Delage, Pascale Picard, Jean-Michel Cardot, et al.. Milnacipran poorly modulates pain in patients suffering from fibromyalgia: a randomized double-blind controlled study. Drug Design, Development and Therapy, 2018, 12, pp.2485-2496. ⟨10.2147/DDDT.S162810⟩. ⟨hal-01870569⟩
Accès au texte intégral et bibtex

https://hal.science/hal-01870569/file/2018_Pickering_Drug_Design_Dev_Ther.pdf


BibTex

2017

ref_biblio
Marion Gougain, Moreau Alain, Rémy Boussageon, Gisèle Pickering, François Gueyffier. Effet antalgique aigu du paracétamol en soins primaires : des preuves incomplètes. Thérapie, 2017, 72 (5), pp.609 – 613. ⟨10.1016/j.therap.2017.02.004⟩. ⟨halshs-01866986⟩
Accès au texte intégral et bibtex

https://shs.hal.science/halshs-01866986/file/Gougain%202017%20-%20Paracetamol%20en%20soins%20primaires%20-%20version%20auteur.pdf


BibTex

ref_biblio
Gisèle Pickering, Elodie Martin, Florence Tiberghien, Claire Delorme, Gérard Mick. Localized neuropathic pain: an expert consensus on local treatments. Drug Design, Development and Therapy, 2017, 11, pp.2709-2718. ⟨10.2147/DDDT.S142630⟩. ⟨hal-01722921⟩
Accès au texte intégral et bibtex

https://univ-lyon1.hal.science/hal-01722921/file/Localized%20neuropathic%20pain%20an%20expert%20consensus%20on%20local%20treatments.pdf


BibTex

ref_biblio
Gisèle Pickering, Véronique Morel. Memantine for the treatment of general neuropathic pain: a narrative review. Fundamental & Clinical Pharmacology, 2017, ⟨10.1111/fcp.12316⟩. ⟨hal-01662479⟩
Accès au bibtex

BibTex
ref_biblio
Gisèle Pickering, Fiammetta Monacelli, Juan Manuel Pérez-Castejón Garrote, Hirondina Guarda, Luis Batalha, et al.. Reliability Study in Five Languages of the Translation of the Pain Observational Scale Algoplus. Pain Medicine, 2017, ⟨10.1093/pm/pnw356⟩. ⟨hal-01662587⟩
Accès au bibtex

BibTex

2015

ref_biblio
Nicolas Bourdel, João Alves, Gisèle Pickering, Irina Ramilo, Horace Roman, et al.. Systematic review of endometriosis pain assessment: how to choose a scale?. Human Reproduction Update, 2015, 21 (1), pp.136-152. ⟨10.1093/humupd/dmu046⟩. ⟨hal-02317130⟩
Accès au bibtex

BibTex
ref_biblio
Gisèle Pickering, Adrian Kastler, Nicolas Macian, Bruno Pereira, Romain Valabregue, et al.. The brain signature of paracetamol in healthy volunteers: a double-blind randomized trial. Drug Design, Development and Therapy, 2015, 9, pp.3853-3862. ⟨10.2147/DDDT.S81004⟩. ⟨hal-01214449⟩
Accès au texte intégral et bibtex

https://hal.sorbonne-universite.fr/hal-01214449/file/DDDT-81004-the-brain-signature-of-paracetamol-in-healthy-volunteers--a-_072315.pdf


BibTex

2014

ref_biblio
Gisèle Pickering, Véronique Morel, Dominique Joly, Christine Villatte, Delphine Roux, et al.. Prevention of post-mastectomy neuropathic pain with memantine: study protocol for a randomized controlled trial. Trials, 2014, 15, pp.331. ⟨10.1186/1745-6215-15-331⟩. ⟨inserm-01122386⟩
Accès au texte intégral et bibtex

https://inserm.hal.science/inserm-01122386/file/1745-6215-15-331.pdf


BibTex

2012

ref_biblio
Estelle Pujos-Guillot, Gisèle Pickering, Bernard Lyan, Gilles Ducheix, Marion Brandolini-Bunlon, et al.. Therapeutic paracetamol treatment in older persons induces dietary and metabolic modifications related to sulfur amino acids. AGE, 2012, 34 (1), pp.181-193. ⟨10.1007/s11357-011-9218-4⟩. ⟨hal-01190472⟩
Accès au texte intégral et bibtex

https://hal.science/hal-01190472/file/2013_Pujos-Guillot_age_%7B2A068988-311D-4933-8D08-03D0288A4EC3%7D.pdf


BibTex

2011

ref_biblio
Gisèle Pickering, E. Schneider, Isabelle Papet, Estelle Pujos-Guillot, B. Pereira, et al.. Acetaminophen metabolism after major surgery: a greater challenge with increasing age. Clinical Pharmacology and Therapeutics, 2011, 90 (5), pp.707 – 711. ⟨10.1038/clpt.2011.176⟩. ⟨hal-02644818⟩
Accès au bibtex

BibTex

Conference papers

2024

ref_biblio
Fabien Wauquier, Line Boutin-Wittrant, Line Pourtau, David Gaudout, Benjamin Moras, et al.. Les métabolites sériques humains circulants dérivés de la consommation d’un extrait de safran (Safr’InsideTM) protègent les neurones du stress oxydatif : considérations pour les troubles dépressifs. Journées Françaises de Nutrition, Société Française de Nutrition, Dec 2024, Strasbourg, France. ⟨hal-04698791⟩
Accès au bibtex

BibTex

2023

ref_biblio
Gaïa Lépine, Marie Tremblay-Franco, François Mariotti, Jérémie David, Marion Courrent, et al.. Exploring the impact of plant protein vs. animal protein-rich diets in men at cardiometabolic risk: insights from plasma metabolome signatures. 3rd Nordic Metabolomics Conference, Oct 2023, Trondheim, Norway. ⟨hal-04354565⟩
Accès au bibtex

BibTex

2021

ref_biblio
Aurélien Viret, Asma Bourafai-Aziez, Fabien F. Wauquier, Line Boutin-Wittrant, Glwadys Charpentier, et al.. Metabolic profiling strategy for determination of the absorption peak of artichoke leaf extract in human enriched serum. 14ème journées scientifiques du RFMF, Nov 2021, Aussois, France. ⟨hal-03529874⟩
Accès au bibtex

BibTex

Poster communications

2024

ref_biblio
Laurent Mosoni, Cécile Gladine, Claire Sulmont-Rossé, Didier Remond, Matthieu Maillot, et al.. Explorer la variabilité interindividuelle de la réponse à l’alimentation dans une population âgée non fragile vivant à domicile : les projets DBSage et MétabotypAGE. Journée scientifique du CIR3, Oct 2024, Clermont-Ferrand, France. ⟨hal-04793148⟩
Accès au bibtex

BibTex

2023

ref_biblio
Gaïa Lépine, Marie Tremblay-Franco, François Mariotti, Jérémie David, Marion Courrent, et al.. Plasma metabolomics reveal metabolite changes compatible with improved metabolic health after 1-month of a plant-rich dietary intervention. NuGOweek 2023, Sep 2023, Senigallia, Italy. ⟨hal-04211898⟩
Accès au bibtex

BibTex

2022

ref_biblio
Gaïa Lépine, François Mariotti, Marie-Anne Verny, Laetitia Guerin-Deremaux, Catherine Lefranc-Millot, et al.. Effet d’une alimentation plus ou moins végétalisée sur la santé cardio-métabolique : un essai clinique randomisé de 2 mois en croisé avec un haut niveau de contrôle nutritionnel. Journées Francophones de la Nutrition 2022, Nov 2022, Toulouse, France. ⟨hal-03891170⟩
Accès au bibtex

BibTex

2017

ref_biblio
P. Sirvent, M. Bargetto, V. Chavanelle, Nicolas Macian, Sylvia Boulliau, et al.. Phase I clinical trial to evaluate TOTUM-63, a botanical complex for managing prediabetes. 77th Scientific Sessions of American Diabetes Association, Jun 2017, San Diego, United States. ⟨hal-01682304⟩
Accès au texte intégral et bibtex

https://uca.hal.science/hal-01682304/file/Poster-ADA-2017-3.pdf


BibTex

Reports

2020

ref_biblio
Hélène Bastuji, Sophie Baudic, Julie Berbis, Didier Bouhassira, Morgiane Bridou, et al.. Fibromyalgie. [Rapport de recherche] Inserm (dir.). Fibromyalgie. Collection Expertise collective. Rapport. Montrouge : EDP Sciences, 2020., Institut national de la santé et de la recherche médicale (INSERM). 2020, Paris : Inserm : Éditions EDP Sciences (ISSN : 0990-7440) / XIV-883 p. ⟨inserm-03384916⟩
Accès au texte intégral et bibtex

https://inserm.hal.science/inserm-03384916/file/Exp-coll_Fibromyalgie_rapport.pdf


BibTex