Giséla DA SILVA BORGES (EN)
NEURO-DOL – UMR1107 INSERM/UCA
2, rue de Braga, 63100, Clermont-Ferrand (FRANCE)
Dr. Giséla DA SILVA BORGES
Engineer
Team Trigeminal Pain and Migraine
gisela.da_silva_borges@-Code to remove to avoid SPAM-uca.fr
+33 4 73 17 73 67, room 244
Research Theme:
I study changes in the electrophysiological activity of Wide Dynamic Range (WDR) neurons in the trigeminal sensory complex as well as neurons in different brain regions in response to painful stimulation in the orofacial and periorbital regions. I also study how different pharmacological targets can act on these changes.
Techniques Used:
Extracellular electrophysiology, immunohistochemistry, stereotaxic surgery, viral manipulation.
Functions:
Design engineer
Responsibilities:
Responsible for medicines in the Dallel team laboratory.
Image:
HAL Publications
Journal articles
2020
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- Meritxell Llorca-Torralba, Fuencisla Pilar-Cuéllar, Gisela da Silva Borges, Juan Mico, Esther Berrocoso. Opioid receptors mRNAs expression and opioids agonist-dependent G-protein activation in the rat brain following neuropathy. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2020, 99, pp.109857. ⟨10.1016/j.pnpbp.2019.109857⟩. ⟨hal-04258370⟩
- Accès au bibtex
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2017
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- Gisela da Silva Borges, Cristina Miguelez, Fani Neto, Juan Antonio Mico, Luisa Ugedo, et al.. Activation of Extracellular Signal-Regulated Kinases (ERK 1/2) in the Locus Coeruleus Contributes to Pain-Related Anxiety in Arthritic Male Rats. International Journal of Neuropsychopharmacology, 2017, 20 (6), pp.463-475. ⟨10.1093/ijnp/pyx005⟩. ⟨hal-04258416⟩
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2016
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- Meritxell Llorca-Torralba, Gisela Borges, Fani Neto, Juan Antonio Mico, Esther Berrocoso. Noradrenergic Locus Coeruleus pathways in pain modulation. Neuroscience, 2016, 338, pp.93-113. ⟨10.1016/j.neuroscience.2016.05.057⟩. ⟨hal-04258248⟩
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2015
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- Gisela Patrícia Borges, Juan Antonio Micó, Fani Lourença Neto, Esther Berrocoso. Corticotropin-Releasing Factor Mediates Pain-Induced Anxiety through the ERK1/2 Signaling Cascade in Locus Coeruleus Neurons. International Journal of Neuropsychopharmacology, 2015, 18 (8), pyv019. ⟨10.1093/ijnp/pyv019⟩. ⟨hal-04329802⟩
- Accès au texte intégral et bibtex
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- ref_biblio
- Gisela Borges, Esther Berrocoso, Juan Antonio Mico, Fani Neto. ERK1/2: Function, signaling and implication in pain and pain-related anxio-depressive disorders. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2015, 60, pp.77-92. ⟨10.1016/j.pnpbp.2015.02.010⟩. ⟨hal-04329814⟩
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2014
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- Gisela Borges, Fani Neto, Juan Antonio Mico, Esther Berrocoso. Reversal of Monoarthritis-induced Affective Disorders by Diclofenac in Rats. Anesthesiology, 2014, 120 (6), pp.1476-1490. ⟨10.1097/ALN.0000000000000177⟩. ⟨hal-04337324⟩
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2012
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- G.S. Borges, E. Berrocoso, A. Ortega-Alvaro, J.A. Mico, F.L. Neto. Extracellular signal‐regulated kinase activation in the chronic constriction injury model of neuropathic pain in anaesthetized rats. European Journal of Pain, 2012, 17 (1), pp.35-45. ⟨10.1002/j.1532-2149.2012.00181.x⟩. ⟨hal-04329830⟩
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2011
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- Cristina Alba-Delgado, Gisela Borges, Pilar Sánchez-Blázquez, Jorge Ortega, Igor Horrillo, et al.. The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain. Psychopharmacology, 2011, 221 (1), pp.53-65. ⟨10.1007/s00213-011-2542-7⟩. ⟨hal-04329835⟩
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- Fani L. Neto, Gisela Borges, Sonia Torres-Sanchez, Juan A. Mico, Esther Berrocoso. Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence. Current Neuropharmacology, 2011, 9 (4), pp.530-552. ⟨10.2174/157015911798376262⟩. ⟨hal-04329841⟩
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Other publications
2018
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- Gisela da Silva Borges, Ravi Shrivastava, Monika Rousse. The Discovery of VB-Gy Filmogen Glycerol Should Revolutionize Hemorrhoidal Treatment in the Future. 2018, pp.J Clin Trials Res, 1(1): 3-4. ⟨hal-04258463⟩
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Poster communications
2023
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- Manon Dussol, Gisela da Silva Borges, Claudie Beaulieu, Philippe Luccarini, Louis Gendron, et al.. Implication of peripheral and central delta opioid receptors in migraine-like headache in rats. International Headache Congress, Sep 2023, SEOUL, France. ⟨hal-04246524⟩
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