Amélie DESCHEEMAEKER

Journal articles

2025

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Manon Dussol, Gisela da Silva Borges, Claudie Beaulieu, Hadir Ghorbel, Amélie Descheemaeker, et al.. Contribution of peripheral and central delta opioid receptors in the relief of migraine‐like headache in female and male rats. British Journal of Pharmacology, 2025, 182 (18), pp.4380-4399. ⟨10.1111/bph.70098⟩. ⟨hal-05281543⟩

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2024

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Maxime Barnet, Amelie Descheemaeker, Lea Favier, Xavier Moisset, Julien Schopp, et al.. Estrous cycle regulates cephalic mechanical sensitivity and sensitization of the trigemino-cervical complex in a female rat model of chronic migraine. Pain, 2024, ⟨10.1097/j.pain.0000000000003459⟩. ⟨hal-04803604⟩

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2022

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Amélie Descheemaeker, Hervé Poras, Michel Wurm, Philippe Luccarini, Tanja Ouimet, et al.. Dual enkephalinase inhibitor PL37 as a potential novel treatment of migraine: evidence from a rat model. Brain – A Journal of Neurology , 2022, 145 (8), ⟨10.1093/brain/awac139⟩. ⟨hal-03643577⟩

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Eric Ducret, Florian Jacquot, Amélie Descheemaeker, Radhouane Dallel, Alain Artola. Chronic facial inflammatory pain-induced anxiety is associated with bilateral deactivation of the rostral anterior cingulate cortex. Brain Research Bulletin, 2022, 184, pp.88-98. ⟨10.1016/j.brainresbull.2022.03.012⟩. ⟨hal-03646725⟩

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Noëmie Mermet-Joret, Cristina Alba-Delgado, Amélie Descheemaeker, Francois Gabrielli, Radhouane Dallel, et al.. Postnatal development of inner lamina II interneurons of the rat medullary dorsal horn. Pain, 2022, 163 (5), pp.984-998. ⟨10.1097/j.pain.0000000000002459⟩. ⟨hal-04487389⟩

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2021

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Alexia Visseq, Amélie Descheemaeker, Karine Hérault, Francis Giraud, Isabelle Abrunhosa-Thomas, et al.. Improved potency of pyridin-2(1H)one derivatives for the treatment of mechanical allodynia. European Journal of Medicinal Chemistry, 2021, 225, pp.113748. ⟨10.1016/j.ejmech.2021.113748⟩. ⟨hal-03334145⟩

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2020

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Alexia Visseq, Amélie Descheemaeker, Nicolas Pinto-Pardo, Lionel Nauton, Vincent Thery, et al.. Pyridin-2(1H)one derivatives: A possible new class of therapeutics for mechanical allodynia. European Journal of Medicinal Chemistry, 2020, 187, pp.111917. ⟨10.1016/j.ejmech.2019.111917⟩. ⟨hal-02444268⟩

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2017

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Radhouane Dallel, Amélie Descheemaeker, Philippe Luccarini. Recurrent administration of the nitric oxide donor, isosorbide dinitrate, induces a persistent cephalic cutaneous hypersensitivity: A model for migraine progression.. Cephalalgia, 2017, ⟨10.1177/0333102417714032⟩. ⟨hal-01680712⟩

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José Maria Ramos Flores, Laurent Devoize, Amélie Descheemaeker, Jean-Louis Molat, Philippe Luccarini, et al.. The nitric oxide donor, isosorbide dinitrate, induces a cephalic cutaneous hypersensitivity, associated with sensitization of the medullary dorsal horn. Neuroscience, 2017, ⟨10.1016/j.neuroscience.2016.12.028⟩. ⟨inserm-01458345⟩

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2016

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Yan Lefèvre, Aurélie Amadio, Peggy Vincent, Amélie Descheemaeker, Stéphane H.R. Oliet, et al.. Effects of glia metabolism inhibition on nociceptive behavioral testing in rats. Data in Brief, 2016, 7, pp.372 – 375. ⟨10.1016/j.dib.2016.02.043⟩. ⟨hal-03126326⟩

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Nathalie Pham-Dang, Amélie Descheemaeker, Radhouane Dallel, Alain Artola. Activation of medullary dorsal horn γ isoform of protein kinase C interneurons is essential to the development of both static and dynamic facial mechanical allodynia. European Journal of Neuroscience, 2016, 43, pp.802 – 810. ⟨10.1111/ejn.13165⟩. ⟨hal-03126324⟩

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2015

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Yan Lefèvre, Aurélie Amadio, Peggy Vincent, Amélie Descheemaeker, Stéphane H.R. Oliet, et al.. Neuropathic pain depends upon d-serine co-activation of spinal NMDA receptors in rats. Neuroscience Letters, 2015, 603, pp.42-47. ⟨10.1016/j.neulet.2015.07.010⟩. ⟨hal-05059614⟩

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Conference papers

2023

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Pauline Murail, Amélie Descheemaeker, Gisela da Silva Borges, Nicolas Pinto-Pardo, Alexia Visseq, et al.. Pyridin-2(1H)one derivatives: A new class of therapeutics for trigeminal pain. International Headache Congress, Sep 2023, séoul, France. ⟨hal-04213873⟩

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2019

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Amélie Descheemaeker, Hervé Poras, T. Ouimet, P. Luccarini, Michel Wurm, et al.. Dual ENKephalinase Inhibitor (DENKI) PL37: A possible new class of migraine therapeutics. XIXth International Headache Congress, Sep 2019, Dublin, Ireland. ⟨hal-04605885⟩

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P. Luccarini, Marine Megemont, Amélie Descheemaeker, Radhouane Dallel, L. Monconduit. Astrocytes contribute to the trigeminal central sensitization and cephalic cutaneous hypersensitivity in rat model of chronic migraine.. NeuroFrance 2019 Congress, 23-24 mai 2019, Marseille (France)., Société des neurosciences, May 2019, MARSEILLE, France. ⟨hal-04605880⟩

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Marine Megemont, Amélie Descheemaeker, Radhouane Dallel, L. Monconduit, P. Luccarini. Astrocytes contribute to the trigeminal central sensitization and cephalic cutaneous hypersensitivity in rat model of chronic migraine.. 15th Symposium de la Recherche du Réseau Douleur, Mar 2019, Paris, France. ⟨hal-04605879⟩

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A. Visseq, A. Descheemaeker, L. Nauton, V. Théry, F. Giraud, et al.. Design and synthesis of new nitrogen-containing heterocycles for the treatment of mechanical allodynia.. Bioheterocycle 2019, XVIII International Conference on Heterocycles in Bioorganic Chemistry, Jun 2019, Gand, Belgium. ⟨hal-02288758⟩

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2018

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Amélie Descheemaeker, Hervé Poras, P. Luccarini, Michel Wurm, Radhouane Dallel. Dual ENKephalinase Inhibitor (DENKI) PL37: A possible new class of migraine therapeutics.. 17th World Congress on Pain., Sep 2018, Boston (MA), United States. ⟨hal-04605849⟩

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Marine Megemont, Amélie Descheemaeker, Radhouane Dallel, Lenaic Monconduit, P. Luccarini. Astrocytes contribute to the trigeminal central sensitization and cephalic cutaneous hypersensitivity in rat model of chronic migraine.. 12th European Headache Federation Congress, Sep 2018, Firenze (Florence), Italy. ⟨hal-04605851⟩

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Patents

2021

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R. Dallel, A. Artola, A. Descheemaeker, F. Anizon, I. Thomas, et al.. Novel pyridin-2(1H)one derivatives, their preparation and their use for the treatment of pain.. France, Patent n° : WO2021064186. 2021. ⟨hal-03212911⟩

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Poster communications

2024

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T. Frazier, A. Visseq, P. Murail, A. Descheemaeker, N. Pinto-Pardo, et al.. Development of pyridine-2(1H)-one derivatives with in vivo activity toward mechanical allodynia.. Journée scientifique du CIR3, Oct 2024, Aubière, France. ⟨hal-04725553⟩

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2023

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P. Moreau, A. Visseq, A. Descheemaeker, N. Pinto-Pardo, K. Herault, et al.. Development of pyridin-2(1H)-one derivatives with in vivo activity toward mechanical allodynia.. 3rd RSC Anglo-Nordic Medicinal Chemistry Symposium, Jun 2023, Snekkersten, Denmark. ⟨hal-04563721⟩

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P. Murail, A. Descheemaeker, N. Pinto Pardo, G. da Silva Borges, A. Visseq, et al.. Pyridin-2(1H)one derivatives: A new class of therapeutics for trigeminal pain.. International Headache Congress, Sep 2023, Séoul (Corée), South Korea. ⟨hal-04563932⟩

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2019

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J Makhoul, L Poncet-Megemont, K Herault, A Descheemaeker, F Gabrielli, et al.. Identifying Central Circuits for Mechanical Pain. I-site CAP20-25 – Séminaire annuel du Challenge 3, Jan 2019, Clermont-Ferrand, France. ⟨hal-04412977⟩

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2011

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Cedric Peirs, A Descheemaeker, A Artola, R Dallel. How can touch become pain: the short-circuit PKCγ. Doctoriales 2011, Jun 2011, Saint-Nectaire, France. ⟨hal-04413042⟩

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