David BALAYSSAC
UMR 1107 INSERM/UCA Neuro-Dol
Facultés de Médecine et Pharmacie
Place Henri Dunant
63001 Clermont-Ferrand
FRANCE
Pr. David BALAYSSAC
Professeur
Equipe Pharmacologie Fondamentale et Clinique de la Douleur, Équipe PFCD – Axe Douleur et Cancer
david.balayssac@-Code to remove to avoid SPAM-uca.fr
+33 4 73 17 80 41
Thématique de Recherche:
- Etude de la physiopathologie des CIPN, et de l’efficacité de nouvelle stratégies thérapeutiques (animal et Homme)
- Etude de biomarqueurs circulants non-invasifs des CIPN (animal et Homme)
- Etude de l’épidémiologie des douleurs et des comorbidités pendant et après le cancer (Homme)
Enseignements:
- Responsable des UEs de Toxicologie spécialisée, Oncologie, et Troubles liés à l’usage de substances psychoactives et dopage, DFASP1, UFR de Pharmacie
- Responsable de l’UE Oncologie à l’officine, 6ème année de Pharmacie, UFR de Pharmacie
- Encadrement de 2 PhD
- Encadrement de 12 Master
Responsabilités:
- Vice-Doyen-Directeur, UFR de Pharmacie
- Responsable du service pédagogique de Toxicologie, UFR de Pharmacie
- Responsable des relations internationales, UFR de Pharmacie
- Responsable du 2ème cycle des études de Pharmacie, UFR de Pharmacie
- Membre de la Commission scientifique spécialisée Neuroscience (CSS4)
- Membre expert du Haut Conseil de l’évaluation de la recherche et de l’enseignement supérieur (HCERES), pédagogie
- Ancien membre du Conseil national des universités (CNU) 81
Sélection d'articles récents:
- Ragusa et al. Study of the relationship between psychoactive substance use and pain in cancer patients and cancer survivors: A French nationwide cross-sectional study. Int J Cancer. 2024 doi: 10.1002/ijc.35006.
- Balayssac et al. Neurofilament light chain in plasma as a sensitive diagnostic biomarker of peripheral neurotoxicity: In Vivo mouse studies with oxaliplatin and paclitaxel – NeuroDeRisk project. Biomed Pharmacother. 2023. doi: 10.1016/j.biopha.2023.115535.
- Selvy et al. Analgesic and preventive effects of donepezil in animal models of chemotherapy-induced peripheral neuropathy: Involvement of spinal muscarinic acetylcholine M2 receptors. Biomed Pharmacother. 2022. doi: 10.1016/j.biopha.2022.112915.
- Selvy et al. Prevalence of Chemotherapy-Induced Peripheral Neuropathy in Multiple Myeloma Patients and its Impact on Quality of Life: A Single Center Cross-Sectional Study. Front Pharmacol. 2021. doi: 10.3389/fphar.2021.637593.
- Selvy M et al. Prevention, diagnosis and management of chemotherapy-induced peripheral neuropathy: a cross-sectional study of French oncologists’ professional practices. Support Care Cancer. 2021. doi: 10.1007/s00520-020-05928-6.
- Selvy et al. Long-Term Prevalence of Sensory Chemotherapy-Induced Peripheral Neuropathy for 5 Years after Adjuvant FOLFOX Chemotherapy to Treat Colorectal Cancer: A Multicenter Cross-Sectional Study. J Clin Med. 2020. doi: 10.3390/jcm9082400.
- Ferrier et al. Cholinergic Neurotransmission in the Posterior Insular Cortex Is Altered in Preclinical Models of Neuropathic Pain: Key Role of Muscarinic M2 Receptors in Donepezil-Induced Antinociception. J Neurosci. 2015. doi: 10.1523/JNEUROSCI.1537-15.2015.
Informations Supplémentaires:
ORCID : 0000-0002-6126-6588
Linkedin : David Balayssac
Linkedin : David Balayssac
Publications HAL
Article dans une revue
2024
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- David Balayssac, Nicolas Kerckhove, Marie Selvy, Bruno Pereira, Coralie Gonneau, et al.. Motor disorders related to oxaliplatin-induced peripheral neuropathy: long-term severity and impact on quality of life. Supportive Care in Cancer, 2024, 32 (7), pp.427. ⟨10.1007/s00520-024-08627-8⟩. ⟨hal-04619673⟩
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- ref_biblio
- Charles Ragusa, Bruno Pereira, David Balayssac. Study of the relationship between psychoactive substance use and pain in cancer patients and cancer survivors: A French nationwide cross‐sectional study. International Journal of Cancer, 2024, ⟨10.1002/ijc.35006⟩. ⟨hal-04577888⟩
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2023
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- David Balayssac, Julie Durif, Céline Lambert, Cristelle Dalbos, Eric Chapuy, et al.. Exploring Serum Biomarkers for Neuropathic Pain in Rat Models of Chemotherapy-Induced Peripheral Neuropathy: A Comparative Pilot Study with Oxaliplatin, Paclitaxel, Bortezomib, and Vincristine. Toxics, 2023, 11 (12), pp.1004. ⟨10.3390/toxics11121004⟩. ⟨hal-04332718⟩
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- David Balayssac, Bruno Pereira, Juliette Desmard, Hugo Viers, Carole Barillon, et al.. Satisfaction of Cancer Patients Treated with Oral Anticancer Medications regarding Dispensing by Community Pharmacists: A Cross-Sectional Study. European Journal of Cancer Care, 2023, 2023, pp.1 – 9. ⟨10.1155/2023/7746349⟩. ⟨hal-04213488⟩
- Accès au texte intégral et bibtex
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- ref_biblio
- David Balayssac, Jérôme Busserolles, Catherine Broto, Cristelle Dalbos, Laetitia Prival, et al.. Neurofilament light chain in plasma as a sensitive diagnostic biomarker of peripheral neurotoxicity: In Vivo mouse studies with oxaliplatin and paclitaxel – NeuroDeRisk project. Biomedicine and Pharmacotherapy, 2023, 167, pp.115535. ⟨10.1016/j.biopha.2023.115535⟩. ⟨hal-04213471⟩
- Accès au texte intégral et bibtex
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- Julie Maraud, Sabrina Bedhomme, Bruno Pereira, Sophie Trévis, Marine Jary, et al.. Self-Medication during and after Cancer: A French Nation-Wide Cross-Sectional Study. Cancers, 2023, 15 (12), pp.3190. ⟨10.3390/cancers15123190⟩. ⟨hal-04213499⟩
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- Edouard Montigné, David Balayssac. Exploring Cholinergic Compounds for Peripheral Neuropathic Pain Management: A Comprehensive Scoping Review of Rodent Model Studies. Pharmaceuticals, 2023, 16 (10), pp.1363. ⟨10.3390/ph16101363⟩. ⟨hal-04285363⟩
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2021
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- David Balayssac, Bruno Pereira, Pierre Cuq, Juliette Douris, Luc Ferrari, et al.. Perception of pharmacy students toward opioid-related disorders and roles of community pharmacists: A French nationwide cross-sectional study. Substance Abuse, 2021, 42 (4), pp.706-715. ⟨10.1080/08897077.2020.1850607⟩. ⟨hal-03077594⟩
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- Frédéric Dutheil, Lenise M. Parreira, Julia Eismann, François-Xavier Lesage, David Balayssac, et al.. Burnout in french general practitioners: a nationwide prospective study. International Journal of Environmental Research and Public Health, 2021, 18 (22), pp.1-16. ⟨10.3390/ijerph182212044⟩. ⟨hal-03483172⟩
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2020
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- Mélissa Cuménal, Marie Selvy, Nicolas Kerckhove, Célian Bertin, Margaux Morez, et al.. The Safety of Medications used to Treat Peripheral Neuropathic Pain, Part 2 (Opioids, Cannabinoids and Other Drugs): review of Double-Blind, Placebo-Controlled, Randomized Clinical Trials. Expert Opinion on Drug Safety, 2020, pp.1-18. ⟨10.1080/14740338.2021.1842871⟩. ⟨hal-02997543⟩
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- Marie Selvy, Mélissa Cuménal, Nicolas Kerckhove, Christine Courteix, Jérôme Busserolles, et al.. The safety of medications used to treat peripheral neuropathic pain, part 1 (antidepressants and antiepileptics): review of double-blind, placebo-controlled, randomized clinical trials. Expert Opinion on Drug Safety, 2020, 19 (6), pp.707-733. ⟨10.1080/14740338.2020.1764934⟩. ⟨hal-02997564⟩
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- ref_biblio
- Marie Selvy, Bruno Pereira, Nicolas Kerckhove, Coralie Gonneau, Gabrielle Feydel, et al.. Long-Term Prevalence of Sensory Chemotherapy-Induced Peripheral Neuropathy for 5 Years after Adjuvant FOLFOX Chemotherapy to Treat Colorectal Cancer: A Multicenter Cross-Sectional Study. Journal of Clinical Medicine, 2020, 9 (8), pp.2400. ⟨10.3390/jcm9082400⟩. ⟨hal-02997588⟩
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2019
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- Damien Bouvier, David Balayssac, Julie Durif, Charline Mourgues, Catherine Sarret, et al.. Assessment of the advantage of the serum S100B protein biomonitoring in the management of paediatric mild traumatic brain injury—PROS100B: protocol of a multicentre unblinded stepped wedge cluster randomised trial. BMJ Open, 2019, 9 (5), pp.e027365. ⟨10.1136/bmjopen-2018-027365⟩. ⟨hal-02237348⟩
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- Nicolas Kerckhove, Jérôme Busserolles, Trevor Stanbury, Bruno Pereira, Valérie Plence, et al.. Effectiveness assessment of riluzole in the prevention of oxaliplatin-induced peripheral neuropathy: RILUZOX-01: protocol of a randomised, parallel, controlled, double-blind and multicentre study by the UNICANCER-AFSOS Supportive Care intergroup. BMJ Open, 2019, 9 (6), pp.e027770. ⟨10.1136/bmjopen-2018-027770⟩. ⟨hal-02325112⟩
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- Catherine Laporte, Céline Lambert, Bruno Pereira, Olivier Blanc, Nicolas Authier, et al.. Cannabis users: Screen systematically, treat individually. A descriptive study of participants in a randomized trial in primary care. PLoS ONE, 2019, 14 (12), pp.e0224867. ⟨10.1371/journal.pone.0224867⟩. ⟨inserm-02406964⟩
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2018
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- David Balayssac, Bruno Pereira, Maxime Darfeuille, Pierre Cuq, Laurent Vernhet, et al.. Use of Psychotropic Medications and Illegal Drugs, and Related Consequences Among French Pharmacy Students – SCEP Study: A Nationwide Cross-Sectional Study. Frontiers in Pharmacology, 2018, 9, pp.725. ⟨10.3389/fphar.2018.00725⟩. ⟨hal-01858850⟩
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- Laura Poupon, Sylvain Lamoine, Vanessa Pereira, David Barriere, Stéphane Lolignier, et al.. Targeting the TREK-1 potassium channel via riluzole to eliminate the neuropathic and depressive-like effects of oxaliplatin. Neuropharmacology, 2018, 140, pp.43-61. ⟨10.1016/j.neuropharm.2018.07.026⟩. ⟨hal-02065469⟩
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2017
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- David Balayssac, Bruno Pereira, Julie Virot, Aurore Collin, David Alapini, et al.. Burnout, associated comorbidities and coping strategies in French community pharmacies—BOP study: A nationwide cross-sectional study. PLoS ONE, 2017, 12 (8), pp.e0182956. ⟨10.1371/journal.pone.0182956⟩. ⟨hal-01662459⟩
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- David Balayssac, Bruno Pereira, Julie Virot, Celine Lambert, Aurore Collin, et al.. Work-related stress, associated comorbidities and stress causes in French community pharmacies: a nationwide cross-sectional study. PeerJ, 2017, 5, pp.e3973. ⟨10.7717/peerj.3973⟩. ⟨hal-01662581⟩
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- David Balayssac, Bruno Pereira, Jean-Etienne Bazin, Bertrand Le Roy, Denis Pezet, et al.. Erratum to: Warmed and humidified carbon dioxide for abdominal laparoscopic surgery: meta-analysis of the current literature. Surgical Endoscopy, 2017, 31 (1), pp.13 – 16. ⟨10.1007/s00464-016-5335-6⟩. ⟨hal-01682151⟩
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- ref_biblio
- Nicolas Kerckhove, Bruno Pereira, Denis Pezet, David Balayssac. Clinical assessment of new antineuropathic strategies for chemotherapy-induced peripheral neuropathy: pain should not be the principal endpoint. Pain, 2017, 158 (1), pp.180-182. ⟨10.1097/j.pain.0000000000000743⟩. ⟨hal-01607744⟩
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- ref_biblio
- Nicolas Kerckhove, Aurore Collin, Sakahlé Condé, Carine Chaleteix, Denis Pezet, et al.. Long-Term Effects, Pathophysiological Mechanisms, and Risk Factors of Chemotherapy-Induced Peripheral Neuropathies: A Comprehensive Literature Review. Frontiers in Pharmacology, 2017, 8, ⟨10.3389/fphar.2017.00086⟩. ⟨hal-01682157⟩
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2016
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- Bertrand Le Roy, Lucie Tixier, Bruno Pereira, Pierre Sauvanet, Emmanuel Buc, et al.. Assessment of the relation between the expression of oxaliplatin transporters in colorectal cancer and response to FOLFOX-4 adjuvant chemotherapy: A case control study. PLoS ONE, 2016, 11 (2), pp.1-12. ⟨10.1371/journal.pone.0148739⟩. ⟨hal-02635623⟩
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2015
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- David Balayssac, Jérémy Ferrier, Bruno Pereira, Brigitte Gillet, Caroline Petorin, et al.. Prevention of oxaliplatin-induced peripheral neuropathy by a polyamine-reduced diet–NEUROXAPOL: protocol of a prospective, randomised, controlled, single-blind and monocentric trial. BMJ Open, 2015, 5 (4), pp.e007479-e007479. ⟨10.1136/bmjopen-2014-007479⟩. ⟨hal-04327774⟩
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- Anne Dubois, Guillaume Carrier, Bruno Pereira, Brigitte Gillet, Jean-Luc Faucheron, et al.. Therapeutic management of complex anal fistulas by installing a nitinol closure clip: study protocol of a multicentric randomised controlled trial—FISCLOSE: Table 1. BMJ Open, 2015, 5 (12), pp.e009884. ⟨10.1136/bmjopen-2015-009884⟩. ⟨hal-04327771⟩
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- ref_biblio
- Jérémy Ferrier, Mathilde Bayet-Robert, Romain Dalmann, Abderrahim El Guerrab, Youssef Aissouni, et al.. Cholinergic Neurotransmission in the Posterior Insular Cortex Is Altered in Preclinical Models of Neuropathic Pain: Key Role of Muscarinic M2 Receptors in Donepezil-Induced Antinociception. Journal of Neuroscience, 2015, 35 (50), pp.16418-16430. ⟨10.1523/JNEUROSCI.1537-15.2015⟩. ⟨hal-04323801⟩
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Communication dans un congrès
2022
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- Margaux Morez, Youssef Aissouni, Laetitia Prival, Julie Barbier, David Balayssac, et al.. Modulation of HCN channel activity in oxaliplatin-induced peripheral neuropathy.. Annual Meeting of French Society of Pharmacology and Therapeutics 2022 (Congrès SFPT 2022), Société Française de Pharmacologie et de Thérapeutique (SFPT), Jun 2022, Lille, France. pp.10-11, CO-004, ⟨10.1111/fcp.12786⟩. ⟨hal-04026980⟩
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Poster de conférence
2019
- ref_biblio
- David Balayssac. Prevention of oxaliplatin-induced peripheral neuropathy by a polyamine-reduced diet: preliminary results of animal and clinical studies. 7th International Congress on Neuropathic Pain (NeuPSIG 2019, May 2019, LONDRE, France. ⟨hal-02363909⟩
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