Denis ARDID (EN)

UMR 1107 INSERM/UCA Neuro-Dol
Facultés de Médecine et Pharmacie
Place Henri Dunant
63001 Clermont-Ferrand
FRANCE

28 place Henri Dunant
63001 Clermont-Ferrand Cedex 1
France

Pr. Denis ARDID

Professor
Fundamental Pharmacology and Pain Clinic Team, Team FPPC – Microbial Metabolites and Chronic Pain Axis

denis.ardid@-Code to remove to avoid SPAM-uca.fr
+33 4 73 17 82 39

HAL Publications

Journal articles

2024

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Sandie Gervason, Mathieu Meleine, Stéphane Lolignier, Maëva Meynier, Valentine Daugey, et al.. Antihyperalgesic properties of gut microbiota: Parabacteroides distasonis as a new probiotic strategy to alleviate chronic abdominal pain. Pain, 2024, 165 (5), pp.e39-e54. ⟨10.1097/j.pain.0000000000003075⟩. ⟨hal-04316524⟩
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2022

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Lauriane Delay, Julie Barbier, Youssef Aissouni, Alexandra Jurczak, Ludivine Boudieu, et al.. Tyrosine kinase type A–specific signalling pathways are critical for mechanical allodynia development and bone alterations in a mouse model of rheumatoid arthritis. Pain, 2022, 163 (7), pp.e837-e849. ⟨10.1097/j.pain.0000000000002492⟩. ⟨hal-04316536⟩
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Geoffroy Mallaret, Amandine Lashermes, Mathieu Meleine, Ludivine Boudieu, Julie Barbier, et al.. Involvement of toll-like receptor 5 on mouse model of colonic hypersensitivity induced by neonatal maternal separation. World Journal of Gastroenterology, 2022, 28 (29), pp.3903-3916. ⟨10.3748/wjg.v28.i29.3903⟩. ⟨hal-03987265⟩
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https://uca.hal.science/hal-03987265/file/WJG-28-3903.pdf


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Maëva Meynier, Elodie Baudu, Nathalie Rolhion, Manon Defaye, Marjolène Straube, et al.. AhR/IL-22 pathway as new target for the treatment of post-infectious irritable bowel syndrome symptoms. Gut microbes, 2022, 14 (1), pp.1-21. ⟨10.1080/19490976.2021.2022997⟩. ⟨hal-03555153⟩
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https://uca.hal.science/hal-03555153/file/2022_Meynier_Gut_Microbes.pdf


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2021

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Jessica Delorme, Célian Bertin, Noémie Delage, Alain Eschalier, Denis Ardid, et al.. Prevalence of chronic pain in opioid-maintained patients using the capture–recapture method: a nationwide population-based study. Pain, 2021, 162 (1), pp.195-202. ⟨10.1097/j.pain.0000000000002011⟩. ⟨hal-04316546⟩
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2020

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Tanguy Chaumette, Lauriane Delay, Julie Barbier, Ludivine Boudieu, Youssef Aissouni, et al.. c-Jun/p38MAPK/ASIC3 pathways specifically activated by nerve growth factor through TrkA are crucial for mechanical allodynia development. Pain, 2020, pp.1. ⟨10.1097/j.pain.0000000000001808⟩. ⟨hal-02464551⟩
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https://hal.science/hal-02464551/file/PAIN-D-19-00901_R2.pdf


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Manon Defaye, Céline Nourrisson, Elodie Baudu, Amandine Lashermes, Maeva Meynier, et al.. Fecal dysbiosis associated with colonic hypersensitivity and behavioral alterations in chronically Blastocystis-infected rats. Scientific Reports, 2020, 10 (1), pp.9146. ⟨10.1038/s41598-020-66156-w⟩. ⟨inserm-02884871⟩
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https://inserm.hal.science/inserm-02884871/file/s41598-020-66156-w.pdf


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Manon Defaye, Sandie Gervason, Christophe Altier, Jean-Yves Berthon, Denis Ardid, et al.. Microbiota: a novel regulator of pain. Journal of Neural Transmission, 2020, 127 (4), pp.445-465. ⟨10.1007/s00702-019-02083-z⟩. ⟨hal-03036258⟩
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2019

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David André Barrière, Al Mahdy Hamieh, Ricardo Magalhães, Amidou Traore, Julie Barbier, et al.. Structural and functional alterations in the retrosplenial cortex following neuropathic pain. Pain, 2019, 160 (10), pp.2241-2254. ⟨10.1097/j.pain.0000000000001610⟩. ⟨hal-04327523⟩
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Celian Bertin, Jessica Delorme, Marie Riquelme, Hélène Peyrière, Alain Eschalier, et al.. Toward a Triadic Approach to Craving in Addictive Disorders. Harvard Review of Psychiatry, 2019, 27 (5), pp.326-331. ⟨10.1097/HRP.0000000000000225⟩. ⟨hal-02384764⟩
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Célian Bertin, Jessica Delorme, Marie Riquelme, Hélène Peyriere, Georges Brousse, et al.. Risk assessment of using off‐label morphine sulfate in a population‐based retrospective cohort of opioid‐dependent patients. British Journal of Clinical Pharmacology, 2019, 86 (12), pp.2338-2348. ⟨10.1111/bcp.14082⟩. ⟨hal-02325453⟩
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Ludivine Boudieu, Sarah Mountadem, Amandine Lashermes, Mathieu Meleine, Lauriane Ulmann, et al.. Blocking α2δ-1 Subunit Reduces Bladder Hypersensitivity and Inflammation in a Cystitis Mouse Model by Decreasing NF-kB Pathway Activation. Frontiers in Pharmacology, 2019, 10, pp.133. ⟨10.3389/fphar.2019.00133⟩. ⟨hal-02324745⟩
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https://hal.science/hal-02324745/file/fphar-10-00133.pdf


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C. Chenaf, J.-L. Kaboré, J. Delorme, Bruno Pereira, A. Mulliez, et al.. Prescription opioid analgesic use in France: Trends and impact on morbidity-mortality. European Journal of Pain, 2019, 23 (1), pp.124-134. ⟨10.1002/ejp.1291⟩. ⟨hal-02323031⟩
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Nicolas Kerckhove, Julien Scanzi, Bruno Pereira, Denis Ardid, Michel Dapoigny. Effectiveness and safety of 5% lidocaine-medicated plaster on localized neuropathic pain after knee surgery: a randomized, double-blind controlled trial. Pain, 2019, 160 (5), pp.1186-1195. ⟨10.1097/j.pain.0000000000001502⟩. ⟨hal-04257309⟩
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Elodie Picard, Frédéric Antonio Carvalho, Francina Agosti, Emmanuel Bourinet, Denis Ardid, et al.. Inhibition of Cav3.2 calcium channels: A new target for colonic hypersensitivity associated with low‐grade inflammation. British Journal of Pharmacology, 2019, 176 (7), pp.950-963. ⟨10.1111/bph.14608⟩. ⟨hal-04317223⟩
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https://hal.science/hal-04317223/file/British%20J%20Pharmacology%20-%202019%20-%20Picard%20-%20Inhibition%20of%20Cav3%202%20calcium%20channels%20A%20new%20target%20for%20colonic%20hypersensitivity%281%29.pdf


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2018

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Chenaf Chouki, Jessica Delorme, Noémie Delage, Denis Ardid, Alain Eschalier, et al.. Prevalence of chronic pain with or without neuropathic characteristics in France using the capture-recapture method: a population-based study.. Pain, 2018, 159 (11), pp.2394-2402. ⟨10.1097/j.pain.0000000000001347⟩. ⟨hal-01926185⟩
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Manon Defaye, Céline Nourrisson, Elodie Baudu, Ivan Warwzyniak, Virginie Bonnin, et al.. Efficient and reproducible experimental infections of rats with Blastocystis spp.. PLoS ONE, 2018, 13 (11), pp.1-15. ⟨10.1371/journal.pone.0207669⟩. ⟨hal-01931278⟩
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https://uca.hal.science/hal-01931278/file/2018_Delaye_Plos_One.pdf


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Jessica Delorme, Chouki Chenaf, Célian Bertin, Marie Riquelme, Alain Eschalier, et al.. Chronic Pain Opioid-Maintained Patients Receive Less Analgesic Opioid Prescriptions. Frontiers in Psychiatry, 2018, 9, pp.335. ⟨10.3389/fpsyt.2018.00335⟩. ⟨hal-04317238⟩
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https://hal.science/hal-04317238/file/fpsyt-09-00335.pdf


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2017

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Youssef Aissouni, Abderrahim El Guerrab, Al Mahdy Hamieh, Jérémy Ferrier, Maryse Chalus, et al.. Acid-Sensing Ion Channel 1a in the amygdala is involved in pain and anxiety-related behaviours associated with arthritis. Scientific Reports, 2017, 7 (1), pp.43617. ⟨10.1038/srep43617⟩. ⟨hal-04317279⟩
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https://hal.science/hal-04317279/file/srep43617.pdf


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Amandine Dupuis, Anne-Sophie Wattiez, Jérémy Pinguet, Damien Richard, Frédéric Libert, et al.. Increasing spinal 5-HT 2A receptor responsiveness mediates anti-allodynic effect and potentiates fluoxetine efficacy in neuropathic rats. Evidence for GABA release. Pharmacological Research, 2017, 118, pp.93-103. ⟨10.1016/j.phrs.2016.09.021⟩. ⟨hal-04317276⟩
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Nicolas Kerckhove, Julien Scanzi, Bruno Pereira, Denis Ardid, Michel Dapoigny. Assessment of the effectiveness and safety of ethosuximide in the treatment of abdominal pain related to irritable bowel syndrome – IBSET: protocol of a randomised, parallel, controlled, double-blind and multicentre trial. BMJ Open, 2017, 7 (7), pp.e015380. ⟨10.1136/bmjopen-2016-015380⟩. ⟨hal-04317249⟩
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Amandine Lashermes, Ludivine Boudieu, Julie Barbier, Benoit Sion, Agathe Gelot, et al.. Adherent-Invasive E. coli enhances colonic hypersensitivity and P2X receptors expression during post-infectious period. Gut microbes, 2017, 9 (1), pp.26-37. ⟨10.1080/19490976.2017.1361091⟩. ⟨hal-04317240⟩
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2016

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Mathieu Meleine, Ludivine Boudieu, Agathe Gelot, Emilie Muller, Amandine Lashermes, et al.. Comparative effects of alpha 2 delta-1 ligands in mouse models of colonic hypersensitivity. World Journal of Gastroenterology, 2016, 22 (31), pp.7111-7123. ⟨10.3748/wjg.v22.i31.7111⟩. ⟨hal-02636301⟩
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https://hal.inrae.fr/hal-02636301/file/2016_Meleine_World%20Journal%20of%20Gastroenterology_1.pdf


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2013

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Amaury François, Nicolas Kerckhove, Mathieu Meleine, Abdelkrim Alloui, Christian Barrère, et al.. State-dependent properties of a new T-type calcium channel blocker enhance CaV3.2 selectivity and support analgesic effects. Pain, 2013, 154 (2), pp.283-293. ⟨10.1016/j.pain.2012.10.023⟩. ⟨hal-02370536⟩
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2012

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Julien Matricon, Agathe Gelot, Monique Etienne, Michel Lazdunski, Emilie Muller, et al.. Spinal cord plasticity and acid‐sensing ion channels involvement in a rodent model of irritable bowel syndrome. European Journal of Pain, 2012, 15 (4), pp.335-343. ⟨10.1016/j.ejpain.2010.08.005⟩. ⟨hal-04320320⟩
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2007

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Christel Rousseaux, Xavier Thuru, Agathe Gelot, Nicolas Barnich, Christel Neut, et al.. Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nature Medicine, 2007, 13 (1), pp.35-37. ⟨10.1038/nm1521⟩. ⟨hal-02667010⟩
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Conference papers

2020

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Maeva Meynier, Elodie Baudu, Nicolas Barnich, Denis Ardid, Jean-Marc Chatel, et al.. Tryptophan derivatives effects via the AhR signaling pathway modulation on host disturbances after a Citrobacter rodentium infection. CELL SYMPOSIA, May 2020, PARIS, France. ⟨hal-03045712⟩
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Poster communications

2021

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Sandie Gervason, Edith Filaire, Mathieu Meleine, Denis Ardid, Jean-Yves Berthon, et al.. Strict anaerobic bacteria involvement in gut-brain axis: A novel regulator of visceral pain and well-being. Federation of Neurgastroenterology & Motility, Apr 2021, adélaïde, Australia. 32, 2020. ⟨hal-03038507⟩
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2020

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Maeva Meynier, Elodie Baudu, Nicolas Barnich, Denis Ardid, J.M. Chatel, et al.. Effects of tryptophan derivatives via the AHR/Il22 signaling pathway modulation on host disturbances in post citrobacter rodentium infection model mimicking irritable bowel syndrome. UEGW 2020, Oct 2020, AMSTERDAM, Netherlands. ⟨hal-03046872⟩
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2019

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Florian Jacquot, Julie Barbier, Denis Ardid, Fabien Marchand. Peripheral ASIC3 activation by lysophosphatidyl-choline induced chronic joint pain and associated anxiety in mice. Neuroscience 2019, Congress of Society of Neuroscience, Oct 2019, CHICAGO, United States. ⟨hal-02363978⟩
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