Pr. Christine COURTEIX

Journal articles

2023

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Nazarine Mokhtar, Stephane Doly, Christine Courteix. Diabetic Neuropathic Pain and Serotonin: What Is New in the Last 15 Years?. Biomedicines, 2023, Pathological Mechanisms in Diabetes 2.0, 11 (7), pp.1924. ⟨10.3390/biomedicines11071924⟩. ⟨hal-04323925⟩

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Nazarine Mokhtar, Marcin Drop, Florian Jacquot, Sylvain Lamoine, Eric Chapuy, et al.. The Constitutive Activity of Spinal 5-HT6 Receptors Contributes to Diabetic Neuropathic Pain in Rats. Biomolecules, 2023, Recent Advances on 5-HT6 Receptors, 13 (2), pp.364. ⟨10.3390/biom13020364⟩. ⟨hal-04094286⟩

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2021

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Christine Courteix, Alain Eschalier, Christophe Mallet. L’évaluation de la douleur chez l’animal de laboratoire. Douleur et Analgésie, 2021, 34 (2), pp.114-122. ⟨10.3166/dea-2021-0145⟩. ⟨hal-03418812⟩

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Stéphane Doly, Pierre-Yves Martin, Christine Courteix. Récepteur 5-HT6 et mTOR. Médecine/Sciences, 2021, 37 (5), pp.547-549. ⟨10.1051/medsci/2021049⟩. ⟨hal-03229327⟩

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Marcin Drop, Florian Jacquot, Vittorio Canale, Séverine Chaumont-Dubel, Maria Walczak, et al.. Neuropathic pain-alleviating activity of novel 5-HT6 receptor inverse agonists derived from 2-aryl-1H-pyrrole-3-carboxamide. Bioorganic Chemistry, 2021, 115, pp.105218. ⟨10.1016/j.bioorg.2021.105218⟩. ⟨hal-03324439⟩

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2020

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Mélissa Cuménal, Marie Selvy, Nicolas Kerckhove, Célian Bertin, Margaux Morez, et al.. The Safety of Medications used to Treat Peripheral Neuropathic Pain, Part 2 (Opioids, Cannabinoids and Other Drugs): review of Double-Blind, Placebo-Controlled, Randomized Clinical Trials. Expert Opinion on Drug Safety, 2020, pp.1-18. ⟨10.1080/14740338.2021.1842871⟩. ⟨hal-02997543⟩

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Pierre-Yves Martin, Stéphane Doly, Al Mahdy Hamieh, Eric Chapuy, Vittorio Canale, et al.. mTOR activation by constitutively active serotonin6 receptors as new paradigm in neuropathic pain and its treatment. Progress in Neurobiology, 2020, 193, pp.101846. ⟨10.1016/j.pneurobio.2020.101846⟩. ⟨hal-02906397⟩

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Marie Selvy, Mélissa Cuménal, Nicolas Kerckhove, Christine Courteix, Jérôme Busserolles, et al.. The safety of medications used to treat peripheral neuropathic pain, part 1 (antidepressants and antiepileptics): review of double-blind, placebo-controlled, randomized clinical trials. Expert Opinion on Drug Safety, 2020, 19 (6), pp.707-733. ⟨10.1080/14740338.2020.1764934⟩. ⟨hal-02997564⟩

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2017

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Chouki Chenaf, Eric Chapuy, Frédéric Libert, Fabien Marchand, Christine Courteix, et al.. Agomelatine: a new opportunity to reduce neuropathic pain. Preclinical evidence.. Pain, 2017, 158 (1), pp.149 – 160. ⟨10.1097/j.pain.0000000000000738⟩. ⟨hal-01659567⟩

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Amandine Dupuis, Anne-Sophie Wattiez, Jérémy Pinguet, Damien Richard, Frédéric Libert, et al.. Increasing spinal 5-HT 2A receptor responsiveness mediates anti-allodynic effect and potentiates fluoxetine efficacy in neuropathic rats. Evidence for GABA release. Pharmacological Research, 2017, 118, pp.93-103. ⟨10.1016/j.phrs.2016.09.021⟩. ⟨hal-04317276⟩

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Lusliany J Rondón, Marie-Chantal Farges, N Davin, B Sion, a M Privat, et al.. L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration. European Journal of Nutrition, 2017, 57 (7), 11 p. ⟨10.1007/s00394-017-1508-x⟩. ⟨hal-01594068⟩

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Anne-Sophie Wattiez, Amandine Dupuis, Anne-Marie Privat, Maryse Chalus, Eric Chapuy, et al.. Disruption of 5-HT 2A -PDZ protein interaction differently affects the analgesic efficacy of SSRI, SNRI and TCA in the treatment of traumatic neuropathic pain in rats. Neuropharmacology, 2017, 125, pp.308-318. ⟨10.1016/j.neuropharm.2017.07.034⟩. ⟨hal-04323800⟩

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2015

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Marion Fauré, Valérie Paulmier, Alice de Boyer Des Roches, Alain Boissy, Claudia Terlouw, et al.. Douleurs animales. 2. Evaluation et traitement de la douleur chez les ruminants. INRA Productions Animales, 2015, 28 (3), pp.217-280. ⟨hal-02635722⟩

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2013

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Naoual Bouzidi, Hemantkumar Deokar, Alexandre Vogrig, Benjamin Boucherle, Isabelle Ripoche, et al.. Identification of PDZ ligands by docking-based virtual screening for the development of novel analgesic agents. Bioorganic and Medicinal Chemistry Letters, 2013, 23, pp.2624-2627. ⟨10.1016/j.bmcl.2013.02.100⟩. ⟨hal-00846217⟩

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Alexandre Vogrig, Liam Dorr, Naoual Bouzidi, Benjamin Boucherle, Anne-Sophie Wattiez, et al.. Structure-Based Design of PDZ Ligands as Inhibitors of 5-HT2A Receptor/PSD-95 PDZ1 Domain Interaction Possessing Anti-hyperalgesic Activity. ACS Chemical Biology, 2013, 8, pp.2209-2216. ⟨10.1021/cb400308u⟩. ⟨hal-00948867⟩

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Anne-Sophie Wattiez, Xavier Pichon, Amandine Dupuis, Alejandro Hernández, Anne-Marie Privat, et al.. Disruption of 5-HT2A Receptor-PDZ Protein Interactions Alleviates Mechanical Hypersensitivity in Carrageenan-Induced Inflammation in Rats. PLoS ONE, 2013, 8 (9), pp.e74661. ⟨10.1371/journal.pone.0074661⟩. ⟨hal-04323765⟩

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2011

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Juliette Descoeur, Vanessa Pereira, Anne Pizzoccaro, Amaury François, Bing Ling, et al.. Oxaliplatin‐induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors. EMBO Molecular Medicine, 2011, 3 (5), pp.266-278. ⟨10.1002/emmm.201100134⟩. ⟨hal-02370551⟩

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2010

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Lusliany Rondón, A. M. Privat, L. Daulhac, N. Davin, André Mazur, et al.. Magnesium attenuates chronic hypersensitivity and spinal cord NMDA receptor phosphorylation in a rat model of diabetic neuropathic pain. The Journal of Physiology, 2010, 588 (21), pp.4205 – 4215. ⟨10.1113/jphysiol.2010.197004⟩. ⟨hal-02662281⟩

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Poster communications

2023

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Nazarine Mokhtar, Marcin Drop, Frédéric Lamaty, Paweł Zajdel, Philippe Marin, et al.. Diabetic neuropathic pain improvement by inhibition of constitutive 5-HT 6 receptor activity in rats. Neuropathic Pain Special Interest Group (NeuPSIG) 2023 International Congress on Neuropathic Pain, Sep 2023, Lisbon, Portugal. ⟨hal-04324131⟩

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2022

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R. Auguste, E. Jagu, C. Courteix, S. Ducki. Targeting PDZ-mediated protein-protein interactions against neuropathic pain.. European School of Medicinal Chemistry ESMEC, 41st Advanced Course of Medicinal Chemistry and Seminar for PhD students, Jul 2022, Urbino, Italy. ⟨hal-04069002⟩

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2021

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R. Auguste, E. Jagu, C. Courteix, A. Dumeige, S. Ducki. Targeting PDZ-mediated protein-protein interactions against neuropathic pain.. 56èmes Rencontres Internationales de Chimie Thérapeutiques (RICT 2021), Jul 2021, Virtual Event, France. ⟨hal-03468434⟩

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